"The wall of distrust between the United States and Cuba seemed indestructible," said Cardinal Jaime Lucas Ortega Alamino, referring to the 52-year-long U.S. embargo against Cuba.

"Nothing, however, is impossible with God, if we do not resign ourselves. Throughout the years, we did not lose hope."

Ortega was speaking at Rome's Basilica of St. John Lateran Feb. 9 during a Mass to mark the 47th anniversary of the founding of the Sant'Egidio Community. The Italian lay movement, whose mission is largely among the poor, operates in more than 70 countries, including Cuba.

After 18 months of secret talks, U.S. President Barack Obama and Cuban President Raul Castro announced in mid-December their decision to normalize diplomatic and trade relations. Both leaders credited Pope Francis with helping to secure the deal. The Pope had been following and supporting the talks. He had also written personal letters to both leaders and the Vatican hosted a secret meeting last fall.

In his homily, Ortega said the Pope's "extraordinary initiative" brought about "the miracle of a thaw" in relations between the two countries and "the end of a time that seemed never-ending."

"My heart is full of great hope for the future of the Cuban people and I am happy to share this joy with you this evening," he told those assembled.

The cardinal also attributed this new period in U.S.-Cuba relations to "patience in weaving dialogue and perseverance in prayer."

"Dialogue is the bearer of good for everyone," he said.

He noted the ongoing conflicts worldwide, calling for prayers for the situations in Ukraine, Syria and Iraq. He said he hoped the sea change in relations between Cuba and the United States could "be contagious to the entire world" so that dialogue may be taken up where there is fighting.