"The children of Syria invite children from all over the world to join in their prayer for peace" on International Children's Day June 1, he said.
Before praying the Angelus May 29, the Pope said Catholic and Orthodox Christians would be taking part together in the special prayer for peace and that the children were "the protagonists" by inviting all the world's children to unite with them in prayer.
The joint Day of Prayer for Peace, sponsored by the Catholic charity Aid to the Church in Need, is one of several initiatives meant to promote peace in Syria.
The Pope's invitation echoes that of Catholic leaders and Orthodox patriarchs in the country, who signed a joint message inviting Christians around the world to join them in praying for peace.
The message says: "We pray to Him — the Christ, the king of the universe, who carries the world in His hand, in the arms of His mother — to bless all the children of Syria. We implore Him, who alone can bring peace: 'Protect and save the children of this land! Hear our prayers, now! Delay no longer in granting peace to our land! Look upon the tears of the children; dry the tears of the mothers; let the cries of grief at last fall silent!'"